loading...| Preferred Name |
Transportation of BoNT Light chain to cytosol |
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Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 The BoNT L chain traverses the H chain channel into the cytosol, refolds, and is released into the cytosol. The complete molecular details of cleavage of the L- H disulfide bond and L chain refolding are not yet known (Pellizzari et al.,1999). The cleavage of host proteins may require the toxins binding to specific recogntion sites as well as cleavage sites (Rossetto et al., 1994). Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 |
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http://purl.obolibrary.org/obo/HINO_0026744 |
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| comment |
Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 The BoNT L chain traverses the H chain channel into the cytosol, refolds, and is released into the cytosol. The complete molecular details of cleavage of the L- H disulfide bond and L chain refolding are not yet known (Pellizzari et al.,1999). The cleavage of host proteins may require the toxins binding to specific recogntion sites as well as cleavage sites (Rossetto et al., 1994). Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 |
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| definition source |
Reactome, http://www.reactome.org Pubmed10212474 Pubmed7984234 Pubmed1634516 |
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http://purl.obolibrary.org/obo/HINO_0004082 http://purl.obolibrary.org/obo/HINO_0004081 |
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Transportation of BoNT Light chain to cytosol |
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HINO:0026744 |
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Transportation of BoNT Light chain to cytosol |
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| seeAlso |
Reactome Database ID Release 43181365 ReactomeREACT_11226 |
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