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Conformational change in BoNT induced by pH |
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Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 The N-terminal half of the BoNT Heavy Chain undergoes conformational changes effected by endosomal pH resulting in ion channel formation (Blaustein et al., 1987). This process has been demonstrated experimentally for BoNT serotypes A and B, but all serotypes are thought to have this property (Pellizzari et al. 1999). Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 |
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http://purl.obolibrary.org/obo/HINO_0026739 |
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Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 The N-terminal half of the BoNT Heavy Chain undergoes conformational changes effected by endosomal pH resulting in ion channel formation (Blaustein et al., 1987). This process has been demonstrated experimentally for BoNT serotypes A and B, but all serotypes are thought to have this property (Pellizzari et al. 1999). Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 |
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Pubmed10518945 Pubmed2424493 Reactome, http://www.reactome.org Pubmed10212474 Pubmed2446925 |
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Conformational change in BoNT induced by pH |
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HINO:0026739 |
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Conformational change in BoNT induced by pH |
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ReactomeREACT_11131 Reactome Database ID Release 43168788 |
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