Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

BoNT Light Chain Type C1 cleaves Syntaxin

Synonyms
Definitions

Syntaxins are involved in the localization (docking) of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxin 1A interacts with SNAP-25 in forming t-SNARE part of SNARE complex. BoNT Type C specifically cleaves Syntaxin 1A although a broader target spectrum is suspected. Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 Edited: Gopinathrao, G, 2006-06-15 22:12:29 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25

ID

http://purl.obolibrary.org/obo/HINO_0026729

comment

Syntaxins are involved in the localization (docking) of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxin 1A interacts with SNAP-25 in forming t-SNARE part of SNARE complex. BoNT Type C specifically cleaves Syntaxin 1A although a broader target spectrum is suspected.

Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11

Edited: Gopinathrao, G, 2006-06-15 22:12:29

Reviewed: Ichtchenko, K, 2007-08-03 18:17:25

definition source

Reactome, http://www.reactome.org

Pubmed8611567

has input

http://purl.obolibrary.org/obo/HINO_0005608

has output

http://purl.obolibrary.org/obo/HINO_0005607

label

BoNT Light Chain Type C1 cleaves Syntaxin

prefixIRI

HINO:0026729

prefLabel

BoNT Light Chain Type C1 cleaves Syntaxin

seeAlso

EC Number: 3.4.24

Reactome Database ID Release 43181567

ReactomeREACT_11195

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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