Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Edited: Shamovsky, V, 2010-02-27 The MAPK level components of this cascade are p38MAPK-alpha, -beta, -gamma and -sigma. All of those isoforms are activated by phosphorylation of the Thr and Tyr in the Thr-Gly-Tyr motif in their activation loops. Reviewed: Gillespie, ME, 2010-02-27 Authored: Shamovsky, V, 2009-12-16

ID

http://purl.obolibrary.org/obo/HINO_0026427

comment

has a Stoichiometric coefficient of 2

Edited: Shamovsky, V, 2010-02-27

The MAPK level components of this cascade are p38MAPK-alpha, -beta, -gamma and -sigma. All of those isoforms are activated by phosphorylation of the Thr and Tyr in the Thr-Gly-Tyr motif in their activation loops.

Reviewed: Gillespie, ME, 2010-02-27

Authored: Shamovsky, V, 2009-12-16

definition source

Reactome, http://www.reactome.org

Pubmed8622669

Pubmed7535770

has input

http://purl.obolibrary.org/obo/HINO_0005284

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/HINO_0005233

http://purl.obolibrary.org/obo/CHEBI_16761

label

activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3

prefixIRI

HINO:0026427

prefLabel

activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3

seeAlso

EC Number: 2.7.112.1

Reactome Database ID Release 43450333

ReactomeREACT_21395

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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