loading...| Preferred Name | Terminal (3' end) cleavage of viral DNA | |
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| Definitions |
Reviewed: Bushman, FD, 2006-10-30 22:19:13 Prior to integration, two nucleotides are removed from each 3' end of the linear viral DNA, thereby exposing recessed 3' hydroxyls. This reaction may serve to remove heterogenous extra bases from the viral DNA end, and to stabilize the IN-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification. Edited: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22 Authored: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0026281 |
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| comment |
Reviewed: Bushman, FD, 2006-10-30 22:19:13 Prior to integration, two nucleotides are removed from each 3' end of the linear viral DNA, thereby exposing recessed 3' hydroxyls. This reaction may serve to remove heterogenous extra bases from the viral DNA end, and to stabilize the IN-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification. Edited: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22 Authored: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22 |
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| definition source |
Pubmed8883604 Reactome, http://www.reactome.org Pubmed1760846 Pubmed2539592 Pubmed16482214 Pubmed9188609 Pubmed8041787 |
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| label |
Terminal (3' end) cleavage of viral DNA |
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| prefixIRI |
HINO:0026281 |
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| prefLabel |
Terminal (3' end) cleavage of viral DNA |
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| seeAlso |
ReactomeREACT_9069 Reactome Database ID Release 43164522 |
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