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Human Interaction Network Ontology
| Preferred Name | Anchoring fibril formation | |
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| Definitions |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Reviewed: Raleigh, Stewart, 2012-10-08 Collagen VII forms anchoring fibrils, composed of antiparallel dimers that connect the dermis to the epidermis (Bruckner-Tuderman 2009, Has & Kern 2010). During fibrillogenesis, the nascent type VII procollagen molecules dimerize in an antiparallel manner. The C-propeptide is then removed by Bone morphogenetic protein 1 (Rattenholl et al. 2002) and the processed antiparallel dimers laterally aggregate (Villone et al. 2008, Gordon & Hahn 2010). Reviewed: Ricard-Blum, Sylvie, 2012-11-19 Reviewed: Kalamajski, Sebastian, 2012-10-08 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0026127 |
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| comment |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Reviewed: Raleigh, Stewart, 2012-10-08 Collagen VII forms anchoring fibrils, composed of antiparallel dimers that connect the dermis to the epidermis (Bruckner-Tuderman 2009, Has & Kern 2010). During fibrillogenesis, the nascent type VII procollagen molecules dimerize in an antiparallel manner. The C-propeptide is then removed by Bone morphogenetic protein 1 (Rattenholl et al. 2002) and the processed antiparallel dimers laterally aggregate (Villone et al. 2008, Gordon & Hahn 2010). Reviewed: Ricard-Blum, Sylvie, 2012-11-19 Reviewed: Kalamajski, Sebastian, 2012-10-08
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| definition source |
Pubmed19945621 Pubmed19116634 Pubmed11986329 Reactome, http://www.reactome.org Pubmed19693541 Pubmed19945617 Pubmed18599485
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| label |
Anchoring fibril formation
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| located_in | ||
| prefixIRI |
HINO:0026127
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| prefLabel |
Anchoring fibril formation
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| seeAlso |
Reactome Database ID Release 432214320 ReactomeREACT_150268
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| has_part |
http://purl.obolibrary.org/obo/HINO_0022361 http://purl.obolibrary.org/obo/HINO_0022355 |
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