loading...| Preferred Name | Addition of a third mannose to the N-glycan precursor by ALG2 | |
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Reviewed: Gagneux, P, 2010-04-16 Edited: Jassal, B, 2009-12-07 A third mannose is added to the N-glycan precursor by ALG2 using its alpha1,6-mannosyltransferase activity. This has been demonstrated experimentally in yeast (O'Reilly MK et al, 2006; Kämpf M et al, 2009); the human reaction is inferred by homology. Defects in ALG2 are the cause for CDG1I (Thiel C et al, 2003). Authored: Dall'Olio, GM, 2009-11-10 |
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http://purl.obolibrary.org/obo/HINO_0025967 |
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Reviewed: Gagneux, P, 2010-04-16 Edited: Jassal, B, 2009-12-07 A third mannose is added to the N-glycan precursor by ALG2 using its alpha1,6-mannosyltransferase activity. This has been demonstrated experimentally in yeast (O'Reilly MK et al, 2006; Kämpf M et al, 2009); the human reaction is inferred by homology. Defects in ALG2 are the cause for CDG1I (Thiel C et al, 2003). Authored: Dall'Olio, GM, 2009-11-10 |
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Pubmed12684507 Reactome, http://www.reactome.org Pubmed19282279 Pubmed16878994 |
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Addition of a third mannose to the N-glycan precursor by ALG2 |
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HINO:0025967 |
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Addition of a third mannose to the N-glycan precursor by ALG2 |
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Reactome Database ID Release 43449718 ReactomeREACT_22383 |
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