loading...| Preferred Name |
Addition of the first mannose to the N-glycan precursor by ALG13/14 |
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| Synonyms |
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| Definitions |
A mannose is added to the N-glycan precursor via a beta-1,4 linkage. The reaction is catalyzed by ALG1 (Takahashi T et al, 2000). Defects in ALG1 lead to congenital disorder of glycosylation type 1K (CDG1K) (Schwarz M et al, 2004; Kranz C et al, 2004; Grubenmann CE et al, 2004). Reviewed: Gagneux, P, 2010-04-16 Edited: Jassal, B, 2009-11-10 Authored: Dall'Olio, GM, 2009-11-10 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0025965 |
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| comment |
A mannose is added to the N-glycan precursor via a beta-1,4 linkage. The reaction is catalyzed by ALG1 (Takahashi T et al, 2000). Defects in ALG1 lead to congenital disorder of glycosylation type 1K (CDG1K) (Schwarz M et al, 2004; Kranz C et al, 2004; Grubenmann CE et al, 2004). Reviewed: Gagneux, P, 2010-04-16 Edited: Jassal, B, 2009-11-10 Authored: Dall'Olio, GM, 2009-11-10 |
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| definition source |
Reactome, http://www.reactome.org Pubmed14973778 Pubmed14709599 Pubmed10704531 Pubmed14973782 |
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| label |
Addition of the first mannose to the N-glycan precursor by ALG13/14 |
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| prefixIRI |
HINO:0025965 |
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| prefLabel |
Addition of the first mannose to the N-glycan precursor by ALG13/14 |
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| seeAlso |
EC Number: 2.4.1.142 Reactome Database ID Release 43446218 ReactomeREACT_22214 |
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