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uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide |
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| Definitions |
Authored: D'Eustachio, P, 2005-04-04 21:01:34 In the endoplasmic reticulum, the precursor form of urokinase plasminogen activator receptor is transamidated at residue 305, replacing the 30 carboxyterminal residues of the protein with an acylated glucosylphosphatidylinositol (acyl-GPI) moiety. The released carboxyterminal propeptide has no known function. The reaction is catalyzed by GPI transamidase, a complex of at least five proteins associated with the lumenal surface of the endoplasmic reticulum membrane (Yu et al. 1997; Ohishi et al. 2001; Hong et al. 2003). Edited: D'Eustachio, P, 0000-00-00 00:00:00 |
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http://purl.obolibrary.org/obo/HINO_0025945 |
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Authored: D'Eustachio, P, 2005-04-04 21:01:34 In the endoplasmic reticulum, the precursor form of urokinase plasminogen activator receptor is transamidated at residue 305, replacing the 30 carboxyterminal residues of the protein with an acylated glucosylphosphatidylinositol (acyl-GPI) moiety. The released carboxyterminal propeptide has no known function. The reaction is catalyzed by GPI transamidase, a complex of at least five proteins associated with the lumenal surface of the endoplasmic reticulum membrane (Yu et al. 1997; Ohishi et al. 2001; Hong et al. 2003). Edited: D'Eustachio, P, 0000-00-00 00:00:00 |
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| definition source |
Pubmed12802054 Reactome, http://www.reactome.org Pubmed9356492 Pubmed11483512 |
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uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide |
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| prefixIRI |
HINO:0025945 |
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uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide |
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| seeAlso |
Reactome Database ID Release 43162836 ReactomeREACT_1777 |
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