Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine

Synonyms
Definitions

Authored: Johansson, HE, 2007-11-28 23:26:30 Reviewed: Jassal, B, 2008-01-28 15:51:00 The reaction of EIF5A, spermidine, and NAD+ to form EIF5A(Dhp), 1,3-diaminopropane, and NADH + H+ is reversible in vitro. Under physiological conditions, the reverse reaction is probably minimized by the rapid, irreversible conversion of FIF5A(Dhp) to EIF5A(Hyp). Edited: D'Eustachio, P, 2007-11-28 23:33:46

ID

http://purl.obolibrary.org/obo/HINO_0025917

comment

Authored: Johansson, HE, 2007-11-28 23:26:30

Reviewed: Jassal, B, 2008-01-28 15:51:00

The reaction of EIF5A, spermidine, and NAD+ to form EIF5A(Dhp), 1,3-diaminopropane, and NADH + H+ is reversible in vitro. Under physiological conditions, the reverse reaction is probably minimized by the rapid, irreversible conversion of FIF5A(Dhp) to EIF5A(Hyp).

Edited: D'Eustachio, P, 2007-11-28 23:33:46

definition source

Reactome, http://www.reactome.org

Pubmed16452303

has input

http://purl.obolibrary.org/obo/CHEBI_15725

http://purl.obolibrary.org/obo/CHEBI_16908

http://purl.obolibrary.org/obo/CHEBI_15378

http://purl.obolibrary.org/obo/HINO_0025225

has output

http://purl.obolibrary.org/obo/CHEBI_16610

http://purl.obolibrary.org/obo/CHEBI_15846

http://purl.obolibrary.org/obo/HINO_0025227

label

EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine

prefixIRI

HINO:0025917

prefLabel

EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine

seeAlso

EC Number: 2.5.1.46

ReactomeREACT_12481

Reactome Database ID Release 43204617

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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