loading...| Preferred Name |
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC |
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| Synonyms |
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| Definitions |
Group II chaperonins enclose substrate proteins following substrate binding through the formation of a "built- in" lid over the central cavity. Upon ATP binding, lid formation is triggered by the transition state of ATP hydrolysis (Meyer, et al., 2003). In the case of CCT-mediated tubulin folding, one or more rounds of ATP hydrolysis are likely required before the association of non-exchangeable GTP with chaperonin-bound alpha tubulin. Reviewed: Cowan, NJ, 2009-01-21 16:47:24 has a Stoichiometric coefficient of 8 Edited: Matthews, L, 2009-02-21 05:37:28 Authored: Matthews, L, 2008-12-01 04:46:41 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0025736 |
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| comment |
Group II chaperonins enclose substrate proteins following substrate binding through the formation of a "built- in" lid over the central cavity. Upon ATP binding, lid formation is triggered by the transition state of ATP hydrolysis (Meyer, et al., 2003). In the case of CCT-mediated tubulin folding, one or more rounds of ATP hydrolysis are likely required before the association of non-exchangeable GTP with chaperonin-bound alpha tubulin. Reviewed: Cowan, NJ, 2009-01-21 16:47:24 has a Stoichiometric coefficient of 8 Edited: Matthews, L, 2009-02-21 05:37:28 Authored: Matthews, L, 2008-12-01 04:46:41 |
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| definition source |
Pubmed12732144 Reactome, http://www.reactome.org |
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| has input | ||
| has output |
http://purl.obolibrary.org/obo/HINO_0008206 |
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| label |
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC |
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| prefixIRI |
HINO:0025736 |
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| prefLabel |
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC |
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| seeAlso |
ReactomeREACT_17032 Reactome Database ID Release 43389954 |
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| subClassOf |