loading...| Preferred Name |
Addition of GlcNAc to the T antigen forms a Core 2 glycoprotein |
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| Definitions |
Reviewed: Ferrer, A, 2011-11-04 Authored: Jassal, B, 2010-07-19 Edited: Jassal, B, 2010-07-19 The human gene GCNT encodes beta-1,6-N-acetylglucosaminyltransferase which mediates core 2 O-glycan branching by the addition of N-acetylgalactosamine, an important step in mucin-type biosynthesis. There are 3 defined members in humans, 1, 3 and 4 (Bierhuizen and Fukuda, 1992; Yeh et al, 1999; Schwientek et al, 2000). Two members (6 and 7) may be part of the family based on sequence similarity. |
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http://purl.obolibrary.org/obo/HINO_0025649 |
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| comment |
Reviewed: Ferrer, A, 2011-11-04 Authored: Jassal, B, 2010-07-19 Edited: Jassal, B, 2010-07-19 The human gene GCNT encodes beta-1,6-N-acetylglucosaminyltransferase which mediates core 2 O-glycan branching by the addition of N-acetylgalactosamine, an important step in mucin-type biosynthesis. There are 3 defined members in humans, 1, 3 and 4 (Bierhuizen and Fukuda, 1992; Yeh et al, 1999; Schwientek et al, 2000). Two members (6 and 7) may be part of the family based on sequence similarity. |
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| definition source |
Pubmed9915862 Pubmed10753916 Reactome, http://www.reactome.org Pubmed1329093 |
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Addition of GlcNAc to the T antigen forms a Core 2 glycoprotein |
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| prefixIRI |
HINO:0025649 |
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Addition of GlcNAc to the T antigen forms a Core 2 glycoprotein |
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| seeAlso |
EC Number: 2.4.1.102 ReactomeREACT_115905 Reactome Database ID Release 43914012 |
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