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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Trimming of the first glucose by glucosidase I | |
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| Definitions |
Edited: Jassal, B, 2010-03-02 After the glycosylated precursor is attached to the protein, the outer alpha-1,2-linked glucose is removed by glucosidase I (MOGS, GCS1 in yeast). This is a mandatory step for the protein folding control and glycan extension, and defects in MOGS are associated with congenital disorder of glycosylation type IIb (CDGIIb) (De Praeter CM et al, 2000; Völker C et al, 2002). Authored: Dall'Olio, GM, 2009-11-10 Reviewed: Gagneux, P, 2010-08-17 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0025389 |
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| comment |
Edited: Jassal, B, 2010-03-02 After the glycosylated precursor is attached to the protein, the outer alpha-1,2-linked glucose is removed by glucosidase I (MOGS, GCS1 in yeast). This is a mandatory step for the protein folding control and glycan extension, and defects in MOGS are associated with congenital disorder of glycosylation type IIb (CDGIIb) (De Praeter CM et al, 2000; Völker C et al, 2002). Authored: Dall'Olio, GM, 2009-11-10 Reviewed: Gagneux, P, 2010-08-17
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| definition source |
Reactome, http://www.reactome.org Pubmed12145188 Pubmed10788335
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| label |
Trimming of the first glucose by glucosidase I
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| prefixIRI |
HINO:0025389
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| prefLabel |
Trimming of the first glucose by glucosidase I
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| seeAlso |
Reactome Database ID Release 43532678 EC Number: 3.2.1.106 ReactomeREACT_23855
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