loading...| Preferred Name | CYP4B1 can 12-hydroxylate arachidonic acid | |
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| Definitions |
Edited: Jassal, B, 2008-05-19 12:57:01 Authored: Jassal, B, 2008-05-19 12:57:01 Injury to the eye's surface provokes an inflammatory response, mediated, in part, by 12-hydroxyeicosanoids. CYP4B1 catalyzes the 12-hydroxylation of arachidonic acid to 12-HETE and 12-HETrE (12-hydroxy-5,8,10,14-eicosatetraenoic acid and 12-hydroxy-5,8,14-eicosatrienoic acid respectively). Both these metabolites possess potent inflammatory and angiogenic properties. The example of 12-HETE formation only is shown here. Reviewed: D'Eustachio, P, 2008-05-28 08:30:54 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0025161 |
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| comment |
Edited: Jassal, B, 2008-05-19 12:57:01 Authored: Jassal, B, 2008-05-19 12:57:01 Injury to the eye's surface provokes an inflammatory response, mediated, in part, by 12-hydroxyeicosanoids. CYP4B1 catalyzes the 12-hydroxylation of arachidonic acid to 12-HETE and 12-HETrE (12-hydroxy-5,8,10,14-eicosatetraenoic acid and 12-hydroxy-5,8,14-eicosatrienoic acid respectively). Both these metabolites possess potent inflammatory and angiogenic properties. The example of 12-HETE formation only is shown here. Reviewed: D'Eustachio, P, 2008-05-28 08:30:54 |
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| definition source |
Reactome, http://www.reactome.org Pubmed15006160 |
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| has input |
http://purl.obolibrary.org/obo/CHEBI_16474 http://purl.obolibrary.org/obo/CHEBI_15379 |
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| has output |
http://purl.obolibrary.org/obo/CHEBI_19138 |
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| label |
CYP4B1 can 12-hydroxylate arachidonic acid |
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| prefixIRI |
HINO:0025161 |
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| prefLabel |
CYP4B1 can 12-hydroxylate arachidonic acid |
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| seeAlso |
ReactomeREACT_13615 Reactome Database ID Release 43211924 |
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