Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

MDC1/NFBD1associates with gamma H2AX at nuclear foci
Synonyms
Definitions

Recruitment of MDC1 to nuclear foci is mediated by H2AX. MDC1 forms complexes with phosphorylated H2AX, promotes efficient phosphorylation of H2AX and controls the formation of BRCA1 and MRN foci (Stewart et al.,2003). Authored: Matthews, L, 2003-11-18 00:00:00

ID

http://purl.obolibrary.org/obo/HINO_0025078

comment

Recruitment of MDC1 to nuclear foci is mediated by H2AX. MDC1 forms complexes with phosphorylated H2AX, promotes efficient phosphorylation of H2AX and controls the formation of BRCA1 and MRN foci (Stewart et al.,2003).

Authored: Matthews, L, 2003-11-18 00:00:00

definition source

Pubmed12607003

Reactome, http://www.reactome.org

Pubmed12607005

has input

http://purl.obolibrary.org/obo/HINO_0008021

http://purl.obolibrary.org/obo/UniProt_Q14676

has output

http://purl.obolibrary.org/obo/HINO_0008018

label

MDC1/NFBD1associates with gamma H2AX at nuclear foci

prefixIRI

HINO:0025078

prefLabel

MDC1/NFBD1associates with gamma H2AX at nuclear foci

seeAlso

Reactome Database ID Release 4383560

ReactomeREACT_1809

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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