Preferred Name | Phosphorylation of NBS1 by ATM | |
Synonyms |
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Definitions |
NSB1 is a component of the MRE11/RAD50/NBS1 complex which acts early in HRR during resection of the double-strand break. In addition, NBS1 is required for activation of the S-phase checkpoint in response to ionizing radiation (IR), ATM-dependent activation of CHK2 and cell survival after exposure to IR. Authored: Matthews, L, 2003-11-18 00:00:00 |
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ID |
http://purl.obolibrary.org/obo/HINO_0025075 |
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comment |
NSB1 is a component of the MRE11/RAD50/NBS1 complex which acts early in HRR during resection of the double-strand break. In addition, NBS1 is required for activation of the S-phase checkpoint in response to ionizing radiation (IR), ATM-dependent activation of CHK2 and cell survival after exposure to IR. Authored: Matthews, L, 2003-11-18 00:00:00 |
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definition source |
Pubmed12861053 Reactome, http://www.reactome.org |
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label |
Phosphorylation of NBS1 by ATM |
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prefixIRI |
HINO:0025075 |
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prefLabel |
Phosphorylation of NBS1 by ATM |
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seeAlso |
ReactomeREACT_2009 Reactome Database ID Release 4375241 |
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subClassOf |