Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Dissociation of dimeric phospho-ATM complexes
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Authored: Matthews, L, 2003-12-10 03:30:00 Autophosphorylation of ATM results in the dissociation of the dimeric/multimeric ATM complex and initiation of ATM kinase activity. Autophosphorylation does not directly regulate ATM kinase activity. Instead, it is the resulting dissociation of ATM oligomers that allows substrates access to the ATM kinase domain.

ID

http://purl.obolibrary.org/obo/HINO_0025072

comment

has a Stoichiometric coefficient of 2

Authored: Matthews, L, 2003-12-10 03:30:00

Autophosphorylation of ATM results in the dissociation of the dimeric/multimeric ATM complex and initiation of ATM kinase activity. Autophosphorylation does not directly regulate ATM kinase activity. Instead, it is the resulting dissociation of ATM oligomers that allows substrates access to the ATM kinase domain.

definition source

Reactome, http://www.reactome.org

Pubmed12556884

has input

http://purl.obolibrary.org/obo/HINO_0008020

has output

http://purl.obolibrary.org/obo/UniProt_Q13315

label

Dissociation of dimeric phospho-ATM complexes

prefixIRI

HINO:0025072

prefLabel

Dissociation of dimeric phospho-ATM complexes

seeAlso

ReactomeREACT_1167

Reactome Database ID Release 4383895

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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