Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks
Synonyms
Definitions

Authored: Matthews, L, 2003-09-07 08:47:00 DNA-PKcs is recruited to the Ku-DNA end complex (Gottlieb and Jackson, 1993), causing Ku to translocate inwards (away from the break) approximately 10 bp (Yoo and Dynan, 1999). This forms the DNA-PK complex (DNA-PKcs plus Ku70/Ku80) at each end of the DNA double strand break.

ID

http://purl.obolibrary.org/obo/HINO_0025061

comment

Authored: Matthews, L, 2003-09-07 08:47:00

DNA-PKcs is recruited to the Ku-DNA end complex (Gottlieb and Jackson, 1993), causing Ku to translocate inwards (away from the break) approximately 10 bp (Yoo and Dynan, 1999). This forms the DNA-PK complex (DNA-PKcs plus Ku70/Ku80) at each end of the DNA double strand break.

definition source

Pubmed10572166

Pubmed8422676

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/UniProt_P78527

http://purl.obolibrary.org/obo/HINO_0007968

has output

http://purl.obolibrary.org/obo/HINO_0007967

label

Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks

prefixIRI

HINO:0025061

prefLabel

Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks

seeAlso

Reactome Database ID Release 4375916

ReactomeREACT_1989

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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