Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

BRCA1 associates with 53BP1at the site of DNA double-strand break
Synonyms
Definitions

At the beginning of this reaction, 1 molecule of '53BP1:H2AX complex at site of double-strand break', and 1 molecule of 'Breast cancer type 1 susceptibility protein' are present. At the end of this reaction, 1 molecule of 'BRCA1:53BP1 complex at site of DNA double-strand break' is present.<br><br> This reaction takes place in the 'nucleus'.<br>

ID

http://purl.obolibrary.org/obo/HINO_0025044

comment

At the beginning of this reaction, 1 molecule of '53BP1:H2AX complex at site of double-strand break', and 1 molecule of 'Breast cancer type 1 susceptibility protein' are present. At the end of this reaction, 1 molecule of 'BRCA1:53BP1 complex at site of DNA double-strand break' is present.

This reaction takes place in the 'nucleus'.

definition source

Reactome, http://www.reactome.org

Pubmed12364621

Pubmed12778123

Pubmed11756551

has input

http://purl.obolibrary.org/obo/HINO_0007957

http://purl.obolibrary.org/obo/UniProt_P38398

has output

http://purl.obolibrary.org/obo/HINO_0007945

label

BRCA1 associates with 53BP1at the site of DNA double-strand break

prefixIRI

HINO:0025044

prefLabel

BRCA1 associates with 53BP1at the site of DNA double-strand break

seeAlso

ReactomeREACT_1259

Reactome Database ID Release 4383570

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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