Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

phenylalanine + tetrahydrobiopterin + O2 => tyrosine + 4a-hydroxytetrahydrobiopterin + H2O
Synonyms
Definitions

Edited: D'Eustachio, P, 2003-06-24 00:00:00 Cytosolic phenylalanine hydroxylase (PAH) catalyzes the reaction of phenylalanine, molecular oxygen and tetrahydrobiopterin to form tyrosine, water, and 4 alpha-hydroxytetrahydrobiopterin. The active form of the enzyme is a homotetramer (Fusetti et al. 1998). Authored: D'Eustachio, P, 2003-06-24 00:00:00

ID

http://purl.obolibrary.org/obo/HINO_0024664

comment

Edited: D'Eustachio, P, 2003-06-24 00:00:00

Cytosolic phenylalanine hydroxylase (PAH) catalyzes the reaction of phenylalanine, molecular oxygen and tetrahydrobiopterin to form tyrosine, water, and 4 alpha-hydroxytetrahydrobiopterin. The active form of the enzyme is a homotetramer (Fusetti et al. 1998).

Authored: D'Eustachio, P, 2003-06-24 00:00:00

definition source

Pubmed9642259

Reactome, http://www.reactome.org

ISBN0079130356

has input

http://purl.obolibrary.org/obo/CHEBI_17295

http://purl.obolibrary.org/obo/CHEBI_15372

http://purl.obolibrary.org/obo/CHEBI_15379

has output

http://purl.obolibrary.org/obo/CHEBI_15374

http://purl.obolibrary.org/obo/CHEBI_17895

label

phenylalanine + tetrahydrobiopterin + O2 => tyrosine + 4a-hydroxytetrahydrobiopterin + H2O

prefixIRI

HINO:0024664

prefLabel

phenylalanine + tetrahydrobiopterin + O2 => tyrosine + 4a-hydroxytetrahydrobiopterin + H2O

seeAlso

EC Number: 1.14.16.1

ReactomeREACT_2

Reactome Database ID Release 4371118

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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