loading...| Preferred Name | PRLR binds SCF beta-TrCP complex | |
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Reviewed: Goffin, V, 2011-11-08 Authored: Jupe, S, 2011-06-13 Phosphorylation of PRLR on Ser-349 by an unidentified kinase enables recruitment of the SCF beta-TrCP ubiquitin ligase complex, which catalyzes ubiquitination of the receptor (Li et al. 2004). This downregulation mechanism is impaired in some forms of breast cancer (Li et al. 2006). Edited: Jupe, S, 2011-10-17 |
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http://purl.obolibrary.org/obo/HINO_0024417 |
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| comment |
Reviewed: Goffin, V, 2011-11-08 Authored: Jupe, S, 2011-06-13 Phosphorylation of PRLR on Ser-349 by an unidentified kinase enables recruitment of the SCF beta-TrCP ubiquitin ligase complex, which catalyzes ubiquitination of the receptor (Li et al. 2004). This downregulation mechanism is impaired in some forms of breast cancer (Li et al. 2006). Edited: Jupe, S, 2011-10-17 |
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| definition source |
Reactome, http://www.reactome.org Pubmed15082796 Pubmed16278670 |
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PRLR binds SCF beta-TrCP complex |
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HINO:0024417 |
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PRLR binds SCF beta-TrCP complex |
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| seeAlso |
Reactome Database ID Release 431370500 ReactomeREACT_115790 |
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