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Human Interaction Network Ontology
| Preferred Name | SAM is sythesized from methionine's reaction with ATP | |
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| Definitions |
Authored: Gopinathrao, G, 2008-05-21 15:52:50 Reviewed: D'Eustachio, P, 2008-06-12 14:43:38 Edited: Gopinathrao, G, 2006-04-27 13:13:48 S-adenosylmethionine (SAM) is an essential metabolite in all cells. SAM is a precursor in the synthesis of polyamines. Methionine adenosyltransferase (MAT; EC 2.5.1.6) catalyzes the only known SAM biosynthetic reaction from methionine and ATP. In mammalian tissues, three different forms of MAT (MAT I, MAT III and MAT II) have been identified that are the product of two different genes (MAT1A and MAT2A). A third gene MAT2B has been identified and is known to be a part of MAT II heterotetramer complex. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0024196 |
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| comment |
Authored: Gopinathrao, G, 2008-05-21 15:52:50 Reviewed: D'Eustachio, P, 2008-06-12 14:43:38 Edited: Gopinathrao, G, 2006-04-27 13:13:48 S-adenosylmethionine (SAM) is an essential metabolite in all cells. SAM is a precursor in the synthesis of polyamines. Methionine adenosyltransferase (MAT; EC 2.5.1.6) catalyzes the only known SAM biosynthetic reaction from methionine and ATP. In mammalian tissues, three different forms of MAT (MAT I, MAT III and MAT II) have been identified that are the product of two different genes (MAT1A and MAT2A). A third gene MAT2B has been identified and is known to be a part of MAT II heterotetramer complex.
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| definition source |
Reactome, http://www.reactome.org Pubmed12163696 Pubmed9175157
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| has input |
http://purl.obolibrary.org/obo/CHEBI_16643 |
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| has output |
http://purl.obolibrary.org/obo/CHEBI_29888 |
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| label |
SAM is sythesized from methionine's reaction with ATP
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| prefixIRI |
HINO:0024196
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| prefLabel |
SAM is sythesized from methionine's reaction with ATP
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| seeAlso |
Reactome Database ID Release 43174391 ReactomeREACT_6819 EC Number: 2.5.1.6
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