Preferred Name | Corticotropin cleavage from POMC | |
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Definitions |
Reviewed: D'Eustachio, P, 2008-11-29 15:53:45 Authored: Jassal, B, 2008-10-01 13:18:42 Corticotropin (adrenocorticotropic hormone, ACTH) is a 39-amino acid polypeptide hormone produced and secreted by the pituitary gland. It is often produced in response to biological stress (along with corticotropin-releasing hormone). Its principal effects are increased production of androgens and cortisol. Corticotropin is processed from the precursor pro-opiomelanocortin (POMC). The enzyme that performs the cleavage of POMC to corticotropin is prohormone convertase 1 (PC1). In addition to corticotropin, POMC is processed into other small, biologically active fragments. These include lipotropins, melanocyte-stimulating hormone and endorphins. Edited: Jassal, B, 2008-11-17 10:09:58 |
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http://purl.obolibrary.org/obo/HINO_0024161 |
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comment |
Reviewed: D'Eustachio, P, 2008-11-29 15:53:45 Authored: Jassal, B, 2008-10-01 13:18:42 Corticotropin (adrenocorticotropic hormone, ACTH) is a 39-amino acid polypeptide hormone produced and secreted by the pituitary gland. It is often produced in response to biological stress (along with corticotropin-releasing hormone). Its principal effects are increased production of androgens and cortisol. Corticotropin is processed from the precursor pro-opiomelanocortin (POMC). The enzyme that performs the cleavage of POMC to corticotropin is prohormone convertase 1 (PC1). In addition to corticotropin, POMC is processed into other small, biologically active fragments. These include lipotropins, melanocyte-stimulating hormone and endorphins. Edited: Jassal, B, 2008-11-17 10:09:58 |
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definition source |
Pubmed14463577 Reactome, http://www.reactome.org Pubmed9207799 |
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label |
Corticotropin cleavage from POMC |
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prefixIRI |
HINO:0024161 |
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prefLabel |
Corticotropin cleavage from POMC |
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seeAlso |
Reactome Database ID Release 43265301 ReactomeREACT_15476 |
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