Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Activated PLC gamma dissociates from the PDGF receptor

Synonyms
Definitions

Reviewed: Heldin, CH, 2008-11-23 19:29:34 Once phosphorylated, PLCgamma dissociates from the receptor. The active enzyme promotes intracelllular signaling by catalysing the hydrolysis of PIP2 to generate the second messengers IP3 and DAG. Authored: Rothfels, K, 2011-08-24

ID

http://purl.obolibrary.org/obo/HINO_0022906

comment

Reviewed: Heldin, CH, 2008-11-23 19:29:34

Once phosphorylated, PLCgamma dissociates from the receptor. The active enzyme promotes intracelllular signaling by catalysing the hydrolysis of PIP2 to generate the second messengers IP3 and DAG.

Authored: Rothfels, K, 2011-08-24

definition source

Reactome, http://www.reactome.org

Pubmed10579907

has input

http://purl.obolibrary.org/obo/HINO_0023281

has output

http://purl.obolibrary.org/obo/HINO_0023295

http://purl.obolibrary.org/obo/UniProt_P19174

label

Activated PLC gamma dissociates from the PDGF receptor

prefixIRI

HINO:0022906

prefLabel

Activated PLC gamma dissociates from the PDGF receptor

seeAlso

ReactomeREACT_111066

Reactome Database ID Release 431524182

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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