Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

PLC-gamma binds to the active receptor
Synonyms
Definitions

Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 PLC-gamma 1 has been shown to bind to phosphorylated Tyr 1021 of the PDGF beta-receptor with high affinity and to Tyr 1009 with low affinity. In the alpha-receptor, Tyr 988 and Tyr 1018 bind PLC-gamma1. Association of PLC-gamma1 with the activated PDGF receptor has been shown to be necessary for its activation.<br> Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

ID

http://purl.obolibrary.org/obo/HINO_0022902

comment

Reviewed: Heldin, CH, 2008-11-23 19:29:34

Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

PLC-gamma 1 has been shown to bind to phosphorylated Tyr 1021 of the PDGF beta-receptor with high affinity and to Tyr 1009 with low affinity. In the alpha-receptor, Tyr 988 and Tyr 1018 bind PLC-gamma1. Association of PLC-gamma1 with the activated PDGF receptor has been shown to be necessary for its activation.

Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

definition source

Pubmed8443409

Reactome, http://www.reactome.org

Pubmed9739761

Pubmed1396585

has input

http://purl.obolibrary.org/obo/HINO_0023295

http://purl.obolibrary.org/obo/UniProt_P19174

has output

http://purl.obolibrary.org/obo/HINO_0023292

label

PLC-gamma binds to the active receptor

prefixIRI

HINO:0022902

prefLabel

PLC-gamma binds to the active receptor

seeAlso

ReactomeREACT_16998

Reactome Database ID Release 43186765

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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