Preferred Name |
PI3K catalyses the phosphorylation of PIP2 to PIP3 |
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Synonyms |
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Definitions |
Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 PI3K's preferred substrate is phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] which is phosphorylated to the trisphosphate [PI(3,4,5)P3]. PI3-kinase and its products have been found to be of importance in PDGF-stimulated actin reorganization, and directed cell movement, as well as in the stimulation of cell growth and inhibition of apoptosis. Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 |
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ID |
http://purl.obolibrary.org/obo/HINO_0022900 |
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comment |
Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 PI3K's preferred substrate is phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] which is phosphorylated to the trisphosphate [PI(3,4,5)P3]. PI3-kinase and its products have been found to be of importance in PDGF-stimulated actin reorganization, and directed cell movement, as well as in the stimulation of cell growth and inhibition of apoptosis. Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 |
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definition source |
Pubmed2466336 Reactome, http://www.reactome.org Pubmed9739761 |
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has input | ||
has output | ||
label |
PI3K catalyses the phosphorylation of PIP2 to PIP3 |
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prefixIRI |
HINO:0022900 |
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prefLabel |
PI3K catalyses the phosphorylation of PIP2 to PIP3 |
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seeAlso |
ReactomeREACT_16877 EC Number: 2.7.1.153 Reactome Database ID Release 43186800 |
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subClassOf |