Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

PI3-kinase binds to the active receptor

Synonyms
Definitions

Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzymes which can phosphorylate phosphoinositides. These bind to and are activated by PDGF receptors. Tyr 740 and tyr 751 in PDGF beta-receptor, and tyr 731 and tyr 742 in PDGF alpha-receptor have been shown to be autophosphorylation sites and to bind PI3-kinase. <br> Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

ID

http://purl.obolibrary.org/obo/HINO_0022898

comment

Reviewed: Heldin, CH, 2008-11-23 19:29:34

Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

Phosphatidylinositol 3'-kinases (PI3Ks) are a family of enzymes which can phosphorylate phosphoinositides. These bind to and are activated by PDGF receptors. Tyr 740 and tyr 751 in PDGF beta-receptor, and tyr 731 and tyr 742 in PDGF alpha-receptor have been shown to be autophosphorylation sites and to bind PI3-kinase.

Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

definition source

Pubmed2466336

Reactome, http://www.reactome.org

Pubmed9739761

Pubmed1374684

has input

http://purl.obolibrary.org/obo/HINO_0023295

http://purl.obolibrary.org/obo/HINO_0006949

has output

http://purl.obolibrary.org/obo/HINO_0011815

label

PI3-kinase binds to the active receptor

prefixIRI

HINO:0022898

prefLabel

PI3-kinase binds to the active receptor

seeAlso

Reactome Database ID Release 43186780

ReactomeREACT_17052

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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