Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Grb7 binds to the active PDGF receptor

Synonyms
Definitions

Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Grb7 an adapter protein contains a single SH2 domain, a pleckstrin homology (PH) domain, and a proline-rich region. Similar to Grb2, Grb7 interacts with phosphorylated tyrosines in pYXNX motifs, including Tyr716 and Tyr775 of the PDGF beta-receptor.

ID

http://purl.obolibrary.org/obo/HINO_0022868

comment

Reviewed: Heldin, CH, 2008-11-23 19:29:34

Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

Grb7 an adapter protein contains a single SH2 domain, a pleckstrin homology (PH) domain, and a proline-rich region. Similar to Grb2, Grb7 interacts with phosphorylated tyrosines in pYXNX motifs, including Tyr716 and Tyr775 of the PDGF beta-receptor.

definition source

Pubmed10508235

Pubmed8940081

Reactome, http://www.reactome.org

Pubmed9739761

has input

http://purl.obolibrary.org/obo/HINO_0023295

http://purl.obolibrary.org/obo/UniProt_Q14451

has output

http://purl.obolibrary.org/obo/HINO_0023231

label

Grb7 binds to the active PDGF receptor

prefixIRI

HINO:0022868

prefLabel

Grb7 binds to the active PDGF receptor

seeAlso

Reactome Database ID Release 43382055

ReactomeREACT_17063

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.