Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos)

Synonyms
Definitions

Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 SOS is the guanine nucleotide exchange factor (GEF) for Ras. SOS activates Ras nucleotide exchange from the inactive form (bound to GDP) to an active form (bound to GTP).<br>

ID

http://purl.obolibrary.org/obo/HINO_0022860

comment

Reviewed: Heldin, CH, 2008-11-23 19:29:34

Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27

SOS is the guanine nucleotide exchange factor (GEF) for Ras. SOS activates Ras nucleotide exchange from the inactive form (bound to GDP) to an active form (bound to GTP).

definition source

Reactome, http://www.reactome.org

Pubmed9739761

Pubmed8388543

has input

http://purl.obolibrary.org/obo/HINO_0006930

http://purl.obolibrary.org/obo/CHEBI_15996

has output

http://purl.obolibrary.org/obo/HINO_0006926

http://purl.obolibrary.org/obo/CHEBI_17552

label

Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos)

prefixIRI

HINO:0022860

prefLabel

Sos-mediated nucleotide exchange of Ras (PDGF receptor:Grb2:Sos)

seeAlso

ReactomeREACT_16923

Reactome Database ID Release 43186834

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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