loading...| Preferred Name |
Crk binds to the active PDGF receptor |
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| Definitions |
Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Crk family of adaptor molecules consists of CrkI with one SH2 and one SH3 domains and CrkII and CrkL with one SH2 and two SH3 domains each. They bind to Tyr762 of the PDGF alpha-receptor and represent the only known SH2-domain containing molecule which binds with significantly higher affinity to the alpha-receptor than to the beta-receptor. Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0022856 |
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| comment |
Reviewed: Heldin, CH, 2008-11-23 19:29:34 Edited: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 Crk family of adaptor molecules consists of CrkI with one SH2 and one SH3 domains and CrkII and CrkL with one SH2 and two SH3 domains each. They bind to Tyr762 of the PDGF alpha-receptor and represent the only known SH2-domain containing molecule which binds with significantly higher affinity to the alpha-receptor than to the beta-receptor. Authored: Garapati, P V, Jassal, B, 2008-11-24 10:14:27 |
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| definition source |
Pubmed10508235 Reactome, http://www.reactome.org Pubmed9739761 Pubmed9546424 |
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| label |
Crk binds to the active PDGF receptor |
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| prefixIRI |
HINO:0022856 |
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| prefLabel |
Crk binds to the active PDGF receptor |
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| seeAlso |
Reactome Database ID Release 43382056 ReactomeREACT_16940 |
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