Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Cross-presentation of soluble exogenous antigens (endosomes)
Synonyms
Definitions

Authored: Garapati, P V, 2011-03-28 Exogenous soluble antigens are cross-presented by dendritic cells, albeit with lower efficiency than for particulate substrates. Soluble antigens destined for cross-presentation are taken up by distinct endocytosis mechanisms which route them into stable early endosomes and then to the cytoplasm for proteasomal degradation and peptide loading. Edited: Garapati, P V, 2011-03-28 Reviewed: Desjardins, M, English, L, 2011-05-13

ID

http://purl.obolibrary.org/obo/HINO_0022395

comment

Authored: Garapati, P V, 2011-03-28

Exogenous soluble antigens are cross-presented by dendritic cells, albeit with lower efficiency than for particulate substrates. Soluble antigens destined for cross-presentation are taken up by distinct endocytosis mechanisms which route them into stable early endosomes and then to the cytoplasm for proteasomal degradation and peptide loading.

Edited: Garapati, P V, 2011-03-28

Reviewed: Desjardins, M, English, L, 2011-05-13

definition source

Reactome, http://www.reactome.org

Pubmed17157489

Pubmed20171863

Pubmed15592474

label

Cross-presentation of soluble exogenous antigens (endosomes)

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0022395

prefLabel

Cross-presentation of soluble exogenous antigens (endosomes)

seeAlso

GENE ONTOLOGYGO:0002479

ReactomeREACT_111056

Reactome Database ID Release 431236978

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0018144

http://purl.obolibrary.org/obo/HINO_0018142

http://purl.obolibrary.org/obo/HINO_0018141

http://purl.obolibrary.org/obo/HINO_0018143

http://purl.obolibrary.org/obo/HINO_0018145

http://purl.obolibrary.org/obo/HINO_0018161

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