loading...| Preferred Name | Signaling by Interleukins | |
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| Definitions |
Interleukins are low molecular weight proteins that bind to cell surface receptors and act in an autocrine and/or paracrine fashion. They were first identified as factors produced by leukocytes but are now known to be produced by many other cells throughout the body. They have pleiotropic effects on cells which bind them, impacting processes such as tissue growth and repair, hematopoietic homeostasis, and multiple levels of the host defense against pathogens where they are an essential part of the immune system. Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-26 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0022245 |
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| comment |
Interleukins are low molecular weight proteins that bind to cell surface receptors and act in an autocrine and/or paracrine fashion. They were first identified as factors produced by leukocytes but are now known to be produced by many other cells throughout the body. They have pleiotropic effects on cells which bind them, impacting processes such as tissue growth and repair, hematopoietic homeostasis, and multiple levels of the host defense against pathogens where they are an essential part of the immune system. Authored: Ray, KP, 2010-05-17 Reviewed: Pinteaux, E, 2010-05-17 Edited: Jupe, S, 2010-05-26 |
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| definition source |
Pubmed12445398 Reactome, http://www.reactome.org Pubmed19302047 |
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| label |
Signaling by Interleukins |
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| located_in | ||
| prefixIRI |
HINO:0022245 |
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| prefLabel |
Signaling by Interleukins |
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| seeAlso |
Reactome Database ID Release 43449147 ReactomeREACT_22232 |
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| has_part |
http://purl.obolibrary.org/obo/HINO_0022223 http://purl.obolibrary.org/obo/HINO_0022228 http://purl.obolibrary.org/obo/HINO_0022240 http://purl.obolibrary.org/obo/HINO_0022238 |