loading...| Preferred Name | IKK complex recruitment mediated by RIP1 | |
| Synonyms |
|
|
| Definitions |
Reviewed: Fitzgerald, Katherine A, 2012-11-13 Receptor-interacting protein 1 (RIP1) mediates the activation of proinflammatory cytokines via intermediate induction of IKK complex in NFkB pathways [Ea et al. 2006]. Poly(I-C) treatment stimulated the recruitment of RIP1, TRAF6, and TAK1 to the TLR3 receptor complex in human embryonic kidney HEK293 transfected with FLAG-tagged TLR3 [Cusson-Hermance et al. 2005]. RIP1 was shown to be dispensable for TRIF-dependent activation of IRF3, which occurs in a TRIF/TBK1/IKKi-dependent manner [Cusson-Hermance et al. 2005, Sato et al. 2003] Edited: Shamovsky, V, 2010-11-15 Reviewed: Gillespie, ME, 2010-11-30 Authored: Shamovsky, V, 2010-06-01 |
|
| ID |
http://purl.obolibrary.org/obo/HINO_0021958 |
|
| comment |
Reviewed: Fitzgerald, Katherine A, 2012-11-13 Receptor-interacting protein 1 (RIP1) mediates the activation of proinflammatory cytokines via intermediate induction of IKK complex in NFkB pathways [Ea et al. 2006]. Poly(I-C) treatment stimulated the recruitment of RIP1, TRAF6, and TAK1 to the TLR3 receptor complex in human embryonic kidney HEK293 transfected with FLAG-tagged TLR3 [Cusson-Hermance et al. 2005]. RIP1 was shown to be dispensable for TRIF-dependent activation of IRF3, which occurs in a TRIF/TBK1/IKKi-dependent manner [Cusson-Hermance et al. 2005, Sato et al. 2003] Edited: Shamovsky, V, 2010-11-15 Reviewed: Gillespie, ME, 2010-11-30 Authored: Shamovsky, V, 2010-06-01 |
|
| definition source |
Pubmed14530355 Pubmed16603398 Reactome, http://www.reactome.org Pubmed16115877 |
|
| label |
IKK complex recruitment mediated by RIP1 |
|
| located_in | ||
| prefixIRI |
HINO:0021958 |
|
| prefLabel |
IKK complex recruitment mediated by RIP1 |
|
| seeAlso |
ReactomeREACT_25374 Reactome Database ID Release 43937041 |
|
| subClassOf | ||
| has_part |
http://purl.obolibrary.org/obo/HINO_0009323 |