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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Fibulin binds elastic fibres | |
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| Definitions |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Fibulins are a family of 7 genes encoding calcium binding glycoproteins with distinct roles in elastogenesis. They are essential for elastic fibre formation, having a role in regulating and organising tropoelastin formation (Yanagisawa & Davis 2010). Fibulins 1-5 all bind elastin (Roark et al. 1995, Sasaki et al. 1999, Kobayashi et al. 2007). Fibulins 2, 4, 5 and 7 also bind fibrillin (Reinhardt et al. 1996, El Hallous et al. 2007, de Vega et al. 2007). Fibulin 6 has a role in the formation of the cleavage furrow during cytokinesis but its binding partners are unclear (Xu & Vogel 2011). Reviewed: Muiznieks, Lisa, 2012-11-02 |
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http://purl.obolibrary.org/obo/HINO_0021715 |
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| comment |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Fibulins are a family of 7 genes encoding calcium binding glycoproteins with distinct roles in elastogenesis. They are essential for elastic fibre formation, having a role in regulating and organising tropoelastin formation (Yanagisawa & Davis 2010). Fibulins 1-5 all bind elastin (Roark et al. 1995, Sasaki et al. 1999, Kobayashi et al. 2007). Fibulins 2, 4, 5 and 7 also bind fibrillin (Reinhardt et al. 1996, El Hallous et al. 2007, de Vega et al. 2007). Fibulin 6 has a role in the formation of the cleavage furrow during cytokinesis but its binding partners are unclear (Xu & Vogel 2011). Reviewed: Muiznieks, Lisa, 2012-11-02
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| definition source |
Pubmed21966563 Reactome, http://www.reactome.org Pubmed7534784 Pubmed17255108 Pubmed20236620 Pubmed17324935 Pubmed17699513 Pubmed8702639 Pubmed10544250
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Fibulin binds elastic fibres
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| prefixIRI |
HINO:0021715
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| prefLabel |
Fibulin binds elastic fibres
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| seeAlso |
Reactome Database ID Release 431592387 ReactomeREACT_150243
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