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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | FBLN1, FBLN2 bind fibronectin | |
| Synonyms |
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| Definitions |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Fibulins are a family of 7 extracellular calcium binding proteins that have developmental roles (Twal et al. 2001). Fibulins 1-5 are found in association with elastic fibers. Fibulin-1 binds fibronectin (Balbona et al. 1992, Tran et al. 1997) suppressing fibronectin-mediated inhibitory effects on cell attachment and spreading (Twal et al. 2001). Fibulin-2 also binds fibronectin (Sasaki et al. 1995). Reviewed: Muiznieks, Lisa, 2012-11-02 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0021714 |
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| comment |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Fibulins are a family of 7 extracellular calcium binding proteins that have developmental roles (Twal et al. 2001). Fibulins 1-5 are found in association with elastic fibers. Fibulin-1 binds fibronectin (Balbona et al. 1992, Tran et al. 1997) suppressing fibronectin-mediated inhibitory effects on cell attachment and spreading (Twal et al. 2001). Fibulin-2 also binds fibronectin (Sasaki et al. 1995). Reviewed: Muiznieks, Lisa, 2012-11-02
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| definition source |
Reactome, http://www.reactome.org Pubmed1400330 Pubmed11792823 Pubmed7500359 Pubmed9278415
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| has input | ||
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| label |
FBLN1, FBLN2 bind fibronectin
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| name |
Fibulin-1 and -2 bind fibronectin
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| prefixIRI |
HINO:0021714
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| prefLabel |
FBLN1, FBLN2 bind fibronectin
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| seeAlso |
Reactome Database ID Release 432537665 ReactomeREACT_150469
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| subClassOf |
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