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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Collagen type XXV ectomain shedding | |
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| Definitions |
Edited: Jupe, S, 2012-11-12 Identified as a component of amyloid plaques in Alzheimer's brain, the ectodomain of type XXV collagen (known as CLAC) is released by furin convertase activity (Hashimoto et al. 2002). The presence of CLAC leads to Abeta fibril bundles that have an increased resistance to proteases (Söderberg et al. 2005). Authored: Jupe, S, 2011-07-12 has a Stoichiometric coefficient of 3 Reviewed: Sorsa, Timo, 2012-10-08 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0021680 |
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| comment |
Edited: Jupe, S, 2012-11-12 Identified as a component of amyloid plaques in Alzheimer's brain, the ectodomain of type XXV collagen (known as CLAC) is released by furin convertase activity (Hashimoto et al. 2002). The presence of CLAC leads to Abeta fibril bundles that have an increased resistance to proteases (Söderberg et al. 2005). Authored: Jupe, S, 2011-07-12 has a Stoichiometric coefficient of 3 Reviewed: Sorsa, Timo, 2012-10-08
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| definition source |
Pubmed15853808 Reactome, http://www.reactome.org Pubmed11927537 Pubmed15615705
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| label |
Collagen type XXV ectomain shedding
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| prefixIRI |
HINO:0021680
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| prefLabel |
Collagen type XXV ectomain shedding
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| seeAlso |
EC Number: 3.4.21 Reactome Database ID Release 432471842 ReactomeREACT_150355
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