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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Fibrillin-1 binds integrins | |
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| Definitions |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Reviewed: Muiznieks, Lisa, 2012-11-02 Fibrillin-1 splice variants that include the RGD sequence located in the fourth 8-cysteine domain mediate cell adhesion, binding integrin alphaVbeta3 (Pfaff et al. 1996), alpha5beta1 (Bax et al. 2003) and alphaVbeta6 (Jovanovic et al. 2008). AlphaVbeta3 has the highest affinity for fibrillin-1. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0021678 |
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| comment |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2012-04-30 Reviewed: Muiznieks, Lisa, 2012-11-02 Fibrillin-1 splice variants that include the RGD sequence located in the fourth 8-cysteine domain mediate cell adhesion, binding integrin alphaVbeta3 (Pfaff et al. 1996), alpha5beta1 (Bax et al. 2003) and alphaVbeta6 (Jovanovic et al. 2008). AlphaVbeta3 has the highest affinity for fibrillin-1.
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| definition source |
Pubmed8617364 Pubmed18363569 Pubmed12807887 Reactome, http://www.reactome.org
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| label |
Fibrillin-1 binds integrins
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| prefixIRI |
HINO:0021678
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| prefLabel |
Fibrillin-1 binds integrins
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| seeAlso |
Reactome Database ID Release 432328037 ReactomeREACT_150256
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