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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Collagen type VII degradation by MMP1,2,3 | |
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| Definitions |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2011-07-12 Type VII collagen is the major collagen component of anchoring fibrils, which are essential for the attachment of the epidermis to the dermis. It is degraded by MMP1 (Seltzer et al. 1989), MMP2 (Seltzer et al. 1989, Sawamura et al. 1991, Karelina et al. 2000) and MMP3 (Sawamura et al. 1991). MMP2 is 3000-fold more active than MMP1 (Seltzer et al. 1989). Reviewed: Sorsa, Timo, 2012-10-08 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0021652 |
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| comment |
Edited: Jupe, S, 2012-11-12 Authored: Jupe, S, 2011-07-12 Type VII collagen is the major collagen component of anchoring fibrils, which are essential for the attachment of the epidermis to the dermis. It is degraded by MMP1 (Seltzer et al. 1989), MMP2 (Seltzer et al. 1989, Sawamura et al. 1991, Karelina et al. 2000) and MMP3 (Sawamura et al. 1991). MMP2 is 3000-fold more active than MMP1 (Seltzer et al. 1989). Reviewed: Sorsa, Timo, 2012-10-08
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| definition source |
Reactome, http://www.reactome.org Pubmed10652000 Pubmed2537292 Pubmed1704217
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Collagen type VII degradation by MMP1,2,3
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| prefixIRI |
HINO:0021652
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Collagen type VII degradation by MMP1,2,3
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| seeAlso |
EC Number: 3.4.21 ReactomeREACT_150453 Reactome Database ID Release 431564120
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