Preferred Name | Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate | |
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Definitions |
The fructose 2,6-bisphosphatase activity of cytosolic phosphofructokinase 2/fructose-2,6-bisphosphatase catalyzes the hydrolysis of fructose 2,6 bisphosphate to form fructose 6-phosphate. Fructose 2,6 bisphosphate is a key allosteric regulator of PFK1. In its absence the activity of PFK1 is reduced while fructose 1,6-bisphosphatase is activated, thus inhibiting glycolysis and favoring gluconeogenesis (Pilkis et al. 1995). Reviewed: Harris, RA, 2008-09-10 18:47:12 |
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http://purl.obolibrary.org/obo/HINO_0019354 |
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comment |
The fructose 2,6-bisphosphatase activity of cytosolic phosphofructokinase 2/fructose-2,6-bisphosphatase catalyzes the hydrolysis of fructose 2,6 bisphosphate to form fructose 6-phosphate. Fructose 2,6 bisphosphate is a key allosteric regulator of PFK1. In its absence the activity of PFK1 is reduced while fructose 1,6-bisphosphatase is activated, thus inhibiting glycolysis and favoring gluconeogenesis (Pilkis et al. 1995). Reviewed: Harris, RA, 2008-09-10 18:47:12 |
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definition source |
Reactome, http://www.reactome.org Pubmed7574501 |
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Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate |
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prefixIRI |
HINO:0019354 |
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prefLabel |
Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate |
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seeAlso |
Reactome Database ID Release 4370262 ReactomeREACT_1084 EC Number: 3.1.3.46 |
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