Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Polyubiquitination of substrate
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Reviewed: Elliott, T, 2011-02-10 Authored: Garapati, P V, 2010-10-29 Edited: Garapati, P V, 2010-10-29 Monoubiquitinated substrate acquires additional ubiquitin modifications in the form of multiple single attachments or a ubiquitin chain. Polyubiquitin chains added through K48 residue of ubiquitin typically targets the substrate for degradation (Raymond et al. 2009).

ID

http://purl.obolibrary.org/obo/HINO_0018269

comment

has a Stoichiometric coefficient of 2

Reviewed: Elliott, T, 2011-02-10

Authored: Garapati, P V, 2010-10-29

Edited: Garapati, P V, 2010-10-29

Monoubiquitinated substrate acquires additional ubiquitin modifications in the form of multiple single attachments or a ubiquitin chain. Polyubiquitin chains added through K48 residue of ubiquitin typically targets the substrate for degradation (Raymond et al. 2009).

definition source

Reactome, http://www.reactome.org

Pubmed16954532

Pubmed19874575

Pubmed19489725

Pubmed12646216

has input

http://purl.obolibrary.org/obo/HINO_0009678

http://purl.obolibrary.org/obo/HINO_0009849

http://purl.obolibrary.org/obo/CHEBI_15422

has output

http://purl.obolibrary.org/obo/CHEBI_29888

http://purl.obolibrary.org/obo/HINO_0009845

http://purl.obolibrary.org/obo/HINO_0024432

http://purl.obolibrary.org/obo/CHEBI_16027

label

Polyubiquitination of substrate

prefixIRI

HINO:0018269

prefLabel

Polyubiquitination of substrate

seeAlso

EC Number: 6.3.2.19

ReactomeREACT_75847

Reactome Database ID Release 43983156

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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