loading...| Preferred Name | Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases | |
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| Definitions |
Some peptides generated by the 26S proteasome are too long to bind to MHC class I molecules. These N-terminal extended precursor peptides may be trimmed by cytosolic aminopeptidases, such as Tripeptidyl peptidase II (TPP2), puromycin-sensitive aminopeptidase (PSA), bleomycin hydrolase (BH), and leucine aminopeptidase (LAP). Reviewed: Elliott, T, 2011-02-10 Authored: Garapati, P V, 2010-10-29 Edited: Garapati, P V, 2010-10-29 |
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http://purl.obolibrary.org/obo/HINO_0018263 |
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| comment |
Some peptides generated by the 26S proteasome are too long to bind to MHC class I molecules. These N-terminal extended precursor peptides may be trimmed by cytosolic aminopeptidases, such as Tripeptidyl peptidase II (TPP2), puromycin-sensitive aminopeptidase (PSA), bleomycin hydrolase (BH), and leucine aminopeptidase (LAP). Reviewed: Elliott, T, 2011-02-10 Authored: Garapati, P V, 2010-10-29 Edited: Garapati, P V, 2010-10-29 |
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| definition source |
Reactome, http://www.reactome.org Pubmed15224092 Pubmed16849449 Pubmed9668046 Pubmed15224091 Pubmed11062501 |
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| label |
Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases |
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| prefixIRI |
HINO:0018263 |
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| prefLabel |
Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases |
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| seeAlso |
ReactomeREACT_75931 EC Number: 3.4.11 Reactome Database ID Release 43983162 |
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