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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0018231
http://purl.obolibrary.org/obo/HINO_0018231
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|---|---|
| Preferred Name | Interaction of beta-2-microglobulin (B2M) chain with class I HC |
| Definitions |
Reviewed: Elliott, T, 2011-02-10
Authored: Garapati, P V, 2010-10-29
Interaction of calnexin (CNX) with MHC class I HC stabilizes it and facilitates the association of the beta2 microglobulin component (B2M). The two chains are linked noncovalently via interaction of B2M and the alpha3 domain of MHC HC. After formation of the HC:B2M heterodimer, the MHC complex dissociates from CNX.
Edited: Garapati, P V, 2010-10-29
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Interaction of beta-2-microglobulin (B2M) chain with class I HC
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| comment |
Reviewed: Elliott, T, 2011-02-10
Authored: Garapati, P V, 2010-10-29
Interaction of calnexin (CNX) with MHC class I HC stabilizes it and facilitates the association of the beta2 microglobulin component (B2M). The two chains are linked noncovalently via interaction of B2M and the alpha3 domain of MHC HC. After formation of the HC:B2M heterodimer, the MHC complex dissociates from CNX.
Edited: Garapati, P V, 2010-10-29
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| prefLabel |
Interaction of beta-2-microglobulin (B2M) chain with class I HC
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| definition source |
Pubmed10064069
Pubmed2450918
Reactome, http://www.reactome.org
Pubmed14681859
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| prefixIRI |
HINO:0018231
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| seeAlso |
Reactome Database ID Release 43983146
ReactomeREACT_75898
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| subClassOf | |
| type | |
| has input | |
| has output |
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