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Human Interaction Network Ontology
| Preferred Name | Disassembly of COPII coated vesicle | |
| Synonyms |
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| Definitions |
Reviewed: Elliott, T, 2011-02-10 Authored: Garapati, P V, 2010-10-29 Edited: Garapati, P V, 2010-10-29 Before the cargo vesicle can fuse with target membrane, the COPII protein coat must be disassembled and its components released into cytosol. This uncoating is triggered by hydrolysis of the bound GTP to produce Sar1p-GDP, which has decreased affinity for the vesicle membrane. Disassociation of Sar1p-GDP from the membrane is followed by the release of the other COPII subunits. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0018168 |
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| comment |
Reviewed: Elliott, T, 2011-02-10 Authored: Garapati, P V, 2010-10-29 Edited: Garapati, P V, 2010-10-29 Before the cargo vesicle can fuse with target membrane, the COPII protein coat must be disassembled and its components released into cytosol. This uncoating is triggered by hydrolysis of the bound GTP to produce Sar1p-GDP, which has decreased affinity for the vesicle membrane. Disassociation of Sar1p-GDP from the membrane is followed by the release of the other COPII subunits.
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| definition source |
Pubmed10825291 Pubmed17316621 Reactome, http://www.reactome.org Pubmed10982397
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| has input |
http://purl.obolibrary.org/obo/HINO_0004354 |
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| has output |
http://purl.obolibrary.org/obo/HINO_0025103 http://purl.obolibrary.org/obo/UniProt_P55735 http://purl.obolibrary.org/obo/HINO_0008653 http://purl.obolibrary.org/obo/CHEBI_15996 http://purl.obolibrary.org/obo/UniProt_Q15436 |
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| label |
Disassembly of COPII coated vesicle
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| prefixIRI |
HINO:0018168
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| prefLabel |
Disassembly of COPII coated vesicle
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| seeAlso |
ReactomeREACT_75799 EC Number: 3.6.5.3 EC Number: 3.6.5.2 EC Number: 3.6.5.1 EC Number: 3.6.5.4 Reactome Database ID Release 43983422
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