Link to this page
Human Interaction Network Ontology
Last uploaded:
June 27, 2014
Jump to:
| Preferred Name | Proteasomal clevage of exogenous antigen | |
| Synonyms |
|
|
| Definitions |
Exogenous antigens are thought to be processed for cross-presentation in much the same manner as endogenous proteins once they enter the cytosolic pathway (Rock et al. 2010). Immunoproteasome components are the major proteases involved in generating the antigenic fragments. The precurssor peptides are further trimmed by cytosolic aminopeptidases and shuttled to ER through TAP for MHC class I loading. Authored: Garapati, P V, 2011-03-28 Edited: Garapati, P V, 2011-03-28 Reviewed: Desjardins, M, English, L, 2011-05-13 |
|
| ID |
http://purl.obolibrary.org/obo/HINO_0018161 |
|
| comment |
Exogenous antigens are thought to be processed for cross-presentation in much the same manner as endogenous proteins once they enter the cytosolic pathway (Rock et al. 2010). Immunoproteasome components are the major proteases involved in generating the antigenic fragments. The precurssor peptides are further trimmed by cytosolic aminopeptidases and shuttled to ER through TAP for MHC class I loading. Authored: Garapati, P V, 2011-03-28 Edited: Garapati, P V, 2011-03-28 Reviewed: Desjardins, M, English, L, 2011-05-13
|
|
| definition source |
Pubmed20028659 Pubmed16818754 Reactome, http://www.reactome.org
|
|
| has input | ||
| has output | ||
| label |
Proteasomal clevage of exogenous antigen
|
|
| prefixIRI |
HINO:0018161
|
|
| prefLabel |
Proteasomal clevage of exogenous antigen
|
|
| seeAlso |
ReactomeREACT_111172 Reactome Database ID Release 431236970
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |