Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

PKA/PKG phosphorylate Rap1GAP2
Synonyms
Definitions

Authored: Akkerman, JW, 2009-06-03 cGMP and cAMP dependent protein kinases (PKG and PKA respectively) phosphorylate the Rap1 GTPase activating RAP1GAP2 at serine 7 (Schultess et al. 2007). This reduces the binding of inhibitory 14-3-3 proteins to RAP1GAP2. Edited: Jupe, S, 2010-09-01 Reviewed: Heemskerk, JW, 2010-09-01

ID

http://purl.obolibrary.org/obo/HINO_0018115

comment

Authored: Akkerman, JW, 2009-06-03

cGMP and cAMP dependent protein kinases (PKG and PKA respectively) phosphorylate the Rap1 GTPase activating RAP1GAP2 at serine 7 (Schultess et al. 2007). This reduces the binding of inhibitory 14-3-3 proteins to RAP1GAP2.

Edited: Jupe, S, 2010-09-01

Reviewed: Heemskerk, JW, 2010-09-01

definition source

Reactome, http://www.reactome.org

Pubmed15632203

has input

http://purl.obolibrary.org/obo/CHEBI_15422

http://purl.obolibrary.org/obo/UniProt_Q684P5

has output

http://purl.obolibrary.org/obo/CHEBI_16761

http://purl.obolibrary.org/obo/UniProt_Q684P5

label

PKA/PKG phosphorylate Rap1GAP2

prefixIRI

HINO:0018115

prefLabel

PKA/PKG phosphorylate Rap1GAP2

seeAlso

ReactomeREACT_23849

EC Number: 2.7.11

Reactome Database ID Release 43913996

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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