loading...| Preferred Name | PI3K phosphorylates PIP2 to PIP3 | |
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| Definitions |
Reviewed: Trowsdale, J, 2008-02-26 12:02:59 Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10 PI3K enzyme bound to adaptor protein TRIM, uses phosphatidylinositol 4,5-bisphosphate (PIP2) as its substrate and phosphorylates it to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). This PIP3 acts as a membrane anchor for the downstream proteins like PDK1 and PKB. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0017845 |
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| comment |
Reviewed: Trowsdale, J, 2008-02-26 12:02:59 Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10 PI3K enzyme bound to adaptor protein TRIM, uses phosphatidylinositol 4,5-bisphosphate (PIP2) as its substrate and phosphorylates it to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). This PIP3 acts as a membrane anchor for the downstream proteins like PDK1 and PKB. |
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| definition source |
Pubmed12660731 Reactome, http://www.reactome.org |
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| label |
PI3K phosphorylates PIP2 to PIP3 |
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| prefixIRI |
HINO:0017845 |
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| prefLabel |
PI3K phosphorylates PIP2 to PIP3 |
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| seeAlso |
ReactomeREACT_12561 EC Number: 2.7.1.153 Reactome Database ID Release 43202365 |
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