loading...| Preferred Name | p-SLP-76 binds ADAP | |
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Edited: Jupe, S, 2009-11-03 Authored: Akkerman, JW, 2009-06-03 Reviewed: Poole, AW, 2009-11-02 Reviewed: Harper, MT, 2009-11-02 Reviewed: Jones, ML, 2009-11-02 SLP-76 inducibly-associates with ADAP (also known as FYN-binding protein or SLAP-130) a hematopoietic-specific adapter protein. ADAP has been implicated in T cell migration and rearrangement of the actin cytoskeleton. In platelets, adhesion to fibrinogen stimulates the association of SLP-76 with ADAP and VASP (Obergfell et al. 2001). ADAP knockout mice exhibit mild thrombocytopenia (Kasirer-Friede et al. 2007). |
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http://purl.obolibrary.org/obo/HINO_0017843 |
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| comment |
Edited: Jupe, S, 2009-11-03 Authored: Akkerman, JW, 2009-06-03 Reviewed: Poole, AW, 2009-11-02 Reviewed: Harper, MT, 2009-11-02 Reviewed: Jones, ML, 2009-11-02 SLP-76 inducibly-associates with ADAP (also known as FYN-binding protein or SLAP-130) a hematopoietic-specific adapter protein. ADAP has been implicated in T cell migration and rearrangement of the actin cytoskeleton. In platelets, adhesion to fibrinogen stimulates the association of SLP-76 with ADAP and VASP (Obergfell et al. 2001). ADAP knockout mice exhibit mild thrombocytopenia (Kasirer-Friede et al. 2007). |
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| definition source |
Pubmed10671560 Reactome, http://www.reactome.org Pubmed10747096 Pubmed17003372 Pubmed9115214 Pubmed11113155 Pubmed11567141 |
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p-SLP-76 binds ADAP |
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HINO:0017843 |
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p-SLP-76 binds ADAP |
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| seeAlso |
Reactome Database ID Release 43430135 ReactomeREACT_20591 |
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