loading...| Preferred Name | Phosphorylation of SLP-76 | |
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| Definitions |
has a Stoichiometric coefficient of 3 Reviewed: Trowsdale, J, 2008-02-26 12:02:59 Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10 Once SLP-76 is recruited to Gads its rapidly phosphorylated on the tyrosine residues in the N-terminal acidic domain. This domain contains three tyrosine phosphorylation sites, Y113, Y128 and Y145. These tyrosine residues are phosphorylated by tyrosine kinase ZAP-70 and these phosphorylated tyrosine residues provide the binding site for the SH2 domains of the incoming signaling proteins like Vav, Itk and PLC-gamma1. |
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http://purl.obolibrary.org/obo/HINO_0017840 |
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| comment |
has a Stoichiometric coefficient of 3 Reviewed: Trowsdale, J, 2008-02-26 12:02:59 Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10 Once SLP-76 is recruited to Gads its rapidly phosphorylated on the tyrosine residues in the N-terminal acidic domain. This domain contains three tyrosine phosphorylation sites, Y113, Y128 and Y145. These tyrosine residues are phosphorylated by tyrosine kinase ZAP-70 and these phosphorylated tyrosine residues provide the binding site for the SH2 domains of the incoming signaling proteins like Vav, Itk and PLC-gamma1. |
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| definition source |
Reactome, http://www.reactome.org Pubmed17652306 |
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Phosphorylation of SLP-76 |
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| prefixIRI |
HINO:0017840 |
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Phosphorylation of SLP-76 |
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| seeAlso |
EC Number: 2.7.10 ReactomeREACT_12615 Reactome Database ID Release 43202216 |
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