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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0017836
http://purl.obolibrary.org/obo/HINO_0017836
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|---|---|
| Preferred Name | Phosphorylation of PLC-gamma1 |
| Definitions |
Three tyrosine residues at positions 771, 783 and 1254 in PLC-gamma1 have been identified as the sites of receptor tyrosine kinase phosphorylation. Of these Y783 and Y1254 are required for activation of PLC-gamma1. The phosphorylation of the tyrosine residues and the activation of PLC-gamma1 is mediated by both Syk tyrosine kinase ZAP-70 and Tec kinase ITK.
has a Stoichiometric coefficient of 3
Reviewed: Trowsdale, J, 2008-02-26 12:02:59
Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Phosphorylation of PLC-gamma1
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|---|---|
| comment |
Three tyrosine residues at positions 771, 783 and 1254 in PLC-gamma1 have been identified as the sites of receptor tyrosine kinase phosphorylation. Of these Y783 and Y1254 are required for activation of PLC-gamma1. The phosphorylation of the tyrosine residues and the activation of PLC-gamma1 is mediated by both Syk tyrosine kinase ZAP-70 and Tec kinase ITK.
has a Stoichiometric coefficient of 3
Reviewed: Trowsdale, J, 2008-02-26 12:02:59
Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
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| prefLabel |
Phosphorylation of PLC-gamma1
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| definition source |
Reactome, http://www.reactome.org
Pubmed11048639
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| prefixIRI |
HINO:0017836
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| seeAlso |
EC Number: 2.7.10
ReactomeREACT_12498
Reactome Database ID Release 43202248
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| subClassOf | |
| type | |
| has input | |
| has output |
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