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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0017789
http://purl.obolibrary.org/obo/HINO_0017789
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|---|---|
| Preferred Name | Translocation of TRAF6 to CBM complex |
| Definitions |
has a Stoichiometric coefficient of 3
Reviewed: Trowsdale, J, 2008-02-26 12:02:59
Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
TRAF6, which plays central role in innate immune responses, is implicated as proximal downstream effector of MALT1. TRAF6 is a member of the TRAF proteins. It contains an N-term RING domain, followed by several Zn finger domains and C-term MATH domain. The MALT1 oligomers bind to TRAF6, induce TRAF6 oligomerization and thereby activate the ubiquitin ligase activity of TRAF6 to polyubiquitinate itself and NEMO.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label | Translocation of TRAF6 to CBM complex
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|---|---|
| comment | has a Stoichiometric coefficient of 3
Reviewed: Trowsdale, J, 2008-02-26 12:02:59
Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
TRAF6, which plays central role in innate immune responses, is implicated as proximal downstream effector of MALT1. TRAF6 is a member of the TRAF proteins. It contains an N-term RING domain, followed by several Zn finger domains and C-term MATH domain. The MALT1 oligomers bind to TRAF6, induce TRAF6 oligomerization and thereby activate the ubiquitin ligase activity of TRAF6 to polyubiquitinate itself and NEMO.
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| prefLabel | Translocation of TRAF6 to CBM complex
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| definition source |
Reactome, http://www.reactome.org
Pubmed15125833
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| prefixIRI | HINO:0017789
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| seeAlso |
ReactomeREACT_12448
Reactome Database ID Release 43202472
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| subClassOf | |
| type | |
| has input | |
| has output |
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